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HELP - Sick South American Puffers :(

Posted: Sat May 16, 2026 3:03 am
by Ksmit454
1. Iron 0, Copper 0, Nitrate 10, nitrite 0, total hardness 75, total alkalinity 0, Carbonate 40, freshwater PH 6.4, ammonia 0.

2. 40 gallon tank, 4 super red apistogram cichlids, 6 South American puffers, 2 guppies, 3 halfbeaks, 5 Cory catfish, 6 ottocinclus catfish, 6 amano shrimp, 1 loach, 1 female betta, 4 nerite snails.

3. Mix of bloodworms, cichlid food, betta pellets, and sinking catfish food. Algae wafer every few days. Done 5 Ich-X treatments following instructions of a 1/3 water change before each new application. Also added Kanaplex, tomorrow is the last dose of 3 again following the label instructions.

4. No new changes to the tank.

5. Aquarium has been set up for probably 6 months now. We cycled it for a few weeks prior to adding fish. We have a nice 70gallon filter on the fish tank, the AC-70 by Fluval. We made sure water parameters were perfect before getting the fish.


We have 6 South American Puffers. Soemthing has been going on with them for weeks. We began to notice small white spots on them all a few weeks ago. We thought it was ich, so we increased the tank temperature for about a week. It didn’t change anything so I began Ich-X treatments. We have done 5 treatments so far. They have continued to get worse - more white dots all over and their mouths look covered/blocked by white fuzz. I began Kanaplex a few days ago, again following the dosage of 3 doses every other day. I read that it may be something else other than ich and that raising the temperature might make it worse. We’ve now lowered the temp but these fish still look horrible. Ideas? Do I keep doing the ich-X treatments? Kanaplex says 3 treatments and tomorrow will be 3 and they’re still horrible. I’m at a loss as to what to do for these fish. And help is greatly appreciated! I’m trying to get photos to attach but I can’t get them to load, my apologies.

Re: HELP - Sick South American Puffers :(

Posted: Sat May 16, 2026 4:25 pm
by Pufferpunk
This species is very prone to Velvet.

Re: HELP - Sick South American Puffers :(

Posted: Sat May 16, 2026 6:32 pm
by Ksmit454
Looking up the symptoms of Velvet, I don’t think that’s what they have. I wish I could get the photos to upload. They have white dots all over their bodies and fins, and fuzz around their mouths. When we increased the temps for a few weeks and did ich treatment it just got much worse. I’ve lowered the temp now to 70/72 degrees F and am treating with Kanaplex but I’ve done the 3 day treatment. I don’t know what to do next.

Re: HELP - Sick South American Puffers :(

Posted: Sun May 17, 2026 11:27 am
by Pufferpunk
Why lower the temp? I would think that would stress the immune system more. Kanaplex is not helping? Did you use the Ich-x at full dosage?

Re: HELP - Sick South American Puffers :(

Posted: Mon May 18, 2026 12:34 am
by Ksmit454
Epistylis. Raising the temps and treating with such-X has only made the spots and fuzz around their mouths worse. Internet says raising temps can make Epistylis worse, which is what’s happened. Just not sure what to do from here for these puffers

Re: HELP - Sick South American Puffers :(

Posted: Mon May 18, 2026 3:42 pm
by Pufferpunk
Never raise the temps. Did you try the Ich-x in normal tropical temps?